Boston University Superfund Research Program

 
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News and Updates

New publication from Project 4 in the Journal of Immunology

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Project 4 researchers Dr. Jennifer Schlezinger and Dr. David Sherr recently published an article titled “An Endogenous Prostaglandin Enhances Environmental Phthalate-Induced Apoptosis in Bone Marrow B Cells: Activation of Distinct but Overlapping Pathways” in the Journal of Immunology. Phthalate esters are used as plasticizers in a variety of polyvinyl chloride products, including toys, i.v. lines, blood bags, and shower curtains. In humans the main phthalate plasticizer (DEHP) is metabolized into a chemical called MEHP.

In this paper Schlezinger and Sherr sought to understand the signaling pathways that allow MEPH and the endogenous prostaglandin 15d-PGJ2 to induce apoptosis (programmed cell death) in bone marrow B cells. After a series of experiments, the authors found that MEPH and 15d-PGJ2 induce apoptosis through overlapping yet separate pathways.

 

List of BU SBRP Laboratory Reagents and Methods Now Available Online

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In an effort to stimulate collaboration and increase the accessibility of research tools, the Research Translation Core has provided a list of lab reagents and tools that have been developed by BU SBRP researchers with support from the Superfund Basic Research Program. As part of our Open Science philosophy, the reagents and tools on this list may be freely distributed. The list of lab reagents and tools with contact information is available here.


Last Updated ( Thursday, 24 July 2008 14:09 )
 

New Publication in the Encyclopedia of Molecular Pharmacology

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Dr. David Waxman (Project 3) recently had an article titled "Nuclear Receptor Regulation of Hepatic Cytochrome P450 Enzymes" published in the 2nd edition of the Encyclopedia of Molecular Pharmacology. In this article Dr. Waxman explains the basic characteristics of P450 induction, provides examples of CYP1, CYP2B, CYP3A, and CYP4A induction, and discusses the pharmacological relevance of P450 induction.

Last Updated ( Thursday, 24 July 2008 14:11 )
 

Consensus Conference Video Available Online

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A video describing background, process, and results of the 2006 Boston Consensus Conference on Human Biomonitoring is now available online. The Consensus Conference gathered a group of 14 Boston area residents together for 3 weekends in the fall 2006 to learn about and consider issues related to biomonitoring, and to have their questions answered by national experts. The results of their deliberations present an important opportunity to provide public input on the topic to policymakers, researchers, advocacy groups, and others.


Boston Consensus Conference on Human Biomonitoring from BUSBRP on Vimeo.

For more information on the 2006 Boston Consensus Conference on Biomonitoring visit: www.biomonitoring06.org.
Last Updated ( Friday, 11 July 2008 11:01 )
 

Conference Call: Wiki Basics

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On Tuesday, July 8, 2008, at 5pm the Research Translation Core will be leading a conference call titled "Wiki Basics: Using public and private wikis to get your message out and enhance collaboration." This is the second conference call in a series of Web 2.0 workshops. A PDF of the presentation is available below:

Wiki Basics: Using public and private wikis to get your message out and enhance collaboration.

For more information about this presentation, or for information on future conference calls, please email This e-mail address is being protected from spambots, you need JavaScript enabled to view it .
Last Updated ( Friday, 11 July 2008 09:17 )
 


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