Boston University Superfund Research Program

• Burnett, K. G., Bain, L. J., Baldwin, W. S., Callard, G. V., Cohen, S., Di Giulio, R. T., Evans, D. H., Gomez-Chiarri, M., Hahn, M. E., Hoover, C. A., Karchner, S. I., Katoh, F., MacLatchy, D. L., Marshall, W. S., Meyer, J. N., Nacci, D. E., Oleksiak, M. F., Rees, B. B., Stegeman, J. J., et al. (2007). Fundulus as the premier teleost model in environmental biology: Opportunities for new insights using genomics. Comparative Biochemistry and Physiology, 2(4), 257-286. PMCID: PMC2128618.

• Carvan, M. J., III, Gallagher, E. P., Goksoyr, A., Hahn, M. E., & Larsson. D. G. J. (2007). Roundtable discussion:  Fish models in toxicology. Zebrafish, 4(1), 9-20.

• Clodfelter, K. H., Miles, G. D., Wauthier, V., Holloway, M. G., Zhang, X., Hodor, P., Ray, W. J., & Waxman, D. J. (2007). Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis. Physiological Genomics, 31, 63-74. PMCID: PMC2586676.

• Engel, K. B., & Callard, G. V. (2007). Endocrinology of leydig cells in nonmammalian vertebrates. In A. H. Payne & M. P. Hardy (Eds.) The leydig cell in health and disease (pp. 207-224). New York: Humana Press.

 

• Goldstone, J. V., Goldstone, H. M. H., Morrison, A. M., Tarrant, A., Kern, S. E., Woodin, B. R., & Stegeman, J. J. (2007). Cytochrome P450 1 genes in early deuterostomes (tunicates and sea urchins) and vertebrates (chicken and frog): Origin and diversification of the CYP1 gene family.  Molecular Biology and Evolution, 24(12), 2619-2631

 

• Greytak, S. R. & Callard, G. V. (2007). Cloning of three estrogen receptors (ER) from killifish (Fundulus heteroclitus): Differences in populations from polluted and reference environments. General and Comparative Endocrinology, 150(1), 174-188.

• Hahn, M. E., & Hestermann, E. V. (2007). Receptor-mediated mechanisms of toxicity. In R. T. Di Giulio & D. E. Hinton (Eds.), The Toxicology of Fishes. London: Taylor & Francis.

                

• Howard, G. J., Schlezinger, J. J., & Webster., T. F. (2007). Interactions of TCDD with AhR partial agonists and a competitive antagonist: Implications for TEFs. Organohalogen Compounds, 69, 1065-1068.

• Jönsson, M. E., Jenny, M. J., Woodin, B. R., Hahn, M. E., & Stegeman, J. J. (2007). Role of AHR2 in the expression of novel cytochrome P450 1 family genes, cell cycle genes, and morphological defects in developing zebrafish exposed to 3,3',4,4',5-pentachlorobiphenyl or 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicological Sciences, 100(1), 180-193.

• Jönsson, M. E., Orrego, R., Woodin, B. R., Goldstone, J. V., & Stegeman, J. J. (2007). Basal and 3,3,’4,4’,5-pentachlorobiphenyl-induced expression of cytochrome P450 1A, 1B and 1C genes in Zebrafish. Toxicology and Applied Pharmacology, 221(1), 29-41.

• Kitana, N., Won, S. J., & Callard, I. P. (2007). Reproductive deficits in male freshwater turtles (Chrysemys picta) from Cape Cod. Biology of Reproduction, 76, 346-352.

• Lutton, B.V.,  Callard, I.P. (2007). Effects of reproductive activity and sex hormones on apoptosis in the epigonal organ of the skate (Leucoraja erinacea). General and Comparative Endocrinology, 154, 75-84.

• Ma, X., Idle, J. R., Malfatti, M. A., Krausz, K. W., Nebert, D. W., Chen, C.-S., Felton, J. S., Waxman, D. J., et al. (2007). Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).  Carcinogenesis, 28(3), 732-737. PMCID: PMC1829392.

• Prasad, J. C., Goldstone, J. V., Camacho, C. J., Vajda, S. & Stegeman, J. J. (2007). Ensemble modeling of substrate binding to cytochromes P450: Analysis of catalytic differences between CYP1A orthologs. Biochemistry, 46(10), 2640-2654.

• Schlezinger, J. J., Emberley, J. K., Bissonnette, S. L., & Sherr, D. H. (2007). An L-Tyrosine derivative and PPARγ agonist, GW7845, activates a multifaceted caspase cascade in bone marrow B cells. Toxicological Sciences, 98(1), 125-136.

• Silberstein, M., Damborsky, J., & Vajda, S. (2007). Exploring the binding sites of the haloalkane dehalogenase DhlA from Xanthobacter autotrophicus GJ10. Biochemistry, 46(32), 9239-9249.

• Sun, L., Chen, C. S., Waxman, D. J., Liu, H., Halpert, J. R., & Kumar, S. (2007).  Re-engineering cytochrome P450 2B11dH for enhanced metabolism of several substrates including the anti-cancer prodrugs cyclophosphamide and ifosfamide. Archive of Biochemistry and Biophysics, 458(2), 167-174. PMCID: PMC1805465.

•  Webster, T. (2007). Bias magnification in ecologic studies: a methodological investigation. Environmental Health, 6:17. PMCID: PMC1963324.

• Wilson, J. Y., Wells, R., Aguilar, A., Borrell, A., Tornero, V., Reijnders, P., Moore, M., & Stegeman, J. J.  (2007).  Correlates of cytochrome P450 1A1 expression in bottlenose dolphin (Tursiops truncatus) integument biopsies. Toxicological Sciences, 97(1), 111-119.