Project Leader, Tom Webster (Boston University School of Public Health),
Co-investigator, Veronica Vieira (Boston University School of Public Health)
Developing improved methods for mapping epidemiologic data on reproductive and developmental outcomes while adjusting for known risk factors.

Project Leader, David J. Waxman (Boston University, Department of Biology)
Studying exposure to xenoestrogens and other endocrine-disrupting chemicals associated with a variety of developmental and reproductive abnormalities.

Project Leader, Jennifer Schlezinger (Boston University School of Public Health)
Determining the molecular mechanism by which individual and complex mixtures of environmental chemicals impair the development of the mammalian immune system.

Project Leader, Mark E. Hahn (Woods Hole Oceanographic Institution)
Co-investigator, Sibel I. Karchner (Woods Hole Oceanographic Institution)
Understanding mechanisms underlying differential sensitivity to the developmental toxicity of halogenated aromatic hydrocarbons (HAHs) that act through the aryl hydrocarbon receptor (AHR).

Project Leader, John J. Stegeman (Woods Hole Oceanographic Institution)
Co-Investigator, Jared V. Goldstone (Woods Hole Oceanographic Institution)
Continuing research in fish to understand the role of cytochrome p450 (CYP) enzymes in toxicity of chemicals during development.

Project Leader, Gloria V. Callard (Boston University, Department of Biology) Co-Investigator, Ann M. Tarrant (Woods Hole Oceanographic Institution)
Investigating the hypothesis that environmental estrogens and dioxins are neurotoxicants by virtue of their ability to disrupt neural estrogen signaling and gene expression during neurodevelopment.

Project Leader, Ian P. Callard (Boston University, Department of Biology)
Examining the components of the hypothalamic-pituitary-gonadal-target organ axis in the fresh-water turtle to determine the site(s) of lesion(s), which cause a demonstrated reproductive deficit in animals in a pond affected by a Superfund site.

Project Leader, Pericles Stavropoulos (Missouri University of Science and Technology)
Providing new and more robust members of a family of mono-iron reagents (P-450 analogs) for remediation of groundwater and soils/sediments contaminated with halogenated and non-halogenated organics of suspected reproductive and developmental consequences.

Project Leader, David M. Ozonoff (Boston University School of Public Health)
Facilitating collaborations between projects and cores.

Project Leader, Sandor Vajda (Boston University, Department of Biomedical Engineering)
Offering computational tools, expertise, and help to certain projects in modeling and analysis of microarray data.

Project Leader, Madeleine Scammell (Boston University School of Public Health)
Seeking to establish collaborative projects with communities, health care providers, and investigators to address environmental health problems related to community exposure to hazardous waste; and to increase public awareness about environmental health problems and solutions.

Project Leader, Madeleine Scammell (Boston University School of Public Health)
Developing mechanisms to communicate with government agencies, to identify and transfer technology developed in the SRP to appropriate stakeholders, and to communicate research findings to broad audiences.

Project Leader, Ian P. Callard (Boston University, Department of Biology)
Facilitating student training, coursework, and distance learning for graduate students in these areas.