Monday, 03 March 2008 19:00
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BU SBRP researcher David Waxman (project 3) recently published a review article titled "Toxicity of ethylene glycol monomethyl ether: impact on testicular gene expression" in the International Journal of Andrology. Ethylene glycol monomethyl ether (EGME) is an industrial solvent that produces methoxyacetic acid (MAA) upon biological oxidation. In this review Dr. Waxman focused on the gene and signaling pathways that are modulated by EGME exposure and their relevance to the molecular mechanisms underlying EGME and MAA testicular toxicity.